1.5.1 Aminosalicylates


  1. Mesalazine tablets are modified release and different brands may have different release characteristics and, therefore, are not interchangeable. Thus, prescribing should be by brand name.
  2. Mesalazine suppositories are a useful alternative to steroid enemas in maintenance therapy.
  3. Sulfasalazine is useful for patients with concomitant arthritis.
  4. None of the newer aminosalicylates are any more effective than sulfasalazine, but may cause fewer side effects.
  5. CSM Warning: It is recommended that patients receiving aminosalicylates should be advised to report any unexplained bleeding, bruising, purpura, sore throat, fever or malaise that occurs during treatment. A blood count should be performed and the drug stopped immediately if there is a suspicion of a blood dyscrasia.
  6. Olsalazine is minimally absorbed in the small bowel and may offer advantages over mesalazine for distal colitis.
  7. Balsalazide should only be prescribed for patients not responding to other aminosalicylates.

Please note, sample information has been entered into Chapters 1 and 2 only and although fairly clinically accurate, it is not guaranteed. The information was entered during April and May 2017 and drugs will have subsequently been randomly added during telephone demonstrations.

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120 tablet (12 x 10 tablets) £22.10
90 tablet (9 x 10 tablets) £16.58
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180 tablet (18 x 10 tablets) £80.75
90 tablet (9 x 10 tablets) £40.38
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50 sachet £30.74
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28 suppository (4 x 7 suppositories) £40.01
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60 sachet £73.78
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7 enema £17.73
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112 capsule
130 capsule £30.42
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112 capsule £144.00
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60 tablet £161.00
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112 tablet £6.74