- Mesalazine tablets are modified release and different brands may have different release characteristics and, therefore, are not interchangeable. Thus, prescribing should be by brand name.
- Mesalazine suppositories are a useful alternative to steroid enemas in maintenance therapy.
- Sulfasalazine is useful for patients with concomitant arthritis.
- None of the newer aminosalicylates are any more effective than sulfasalazine, but may cause fewer side effects.
- CSM Warning: It is recommended that patients receiving aminosalicylates should be advised to report any unexplained bleeding, bruising, purpura, sore throat, fever or malaise that occurs during treatment. A blood count should be performed and the drug stopped immediately if there is a suspicion of a blood dyscrasia.
- Olsalazine is minimally absorbed in the small bowel and may offer advantages over mesalazine for distal colitis.
- Balsalazide should only be prescribed for patients not responding to other aminosalicylates.
Please note, sample information has been entered into Chapters 1 and 2 only and although fairly clinically accurate, it is not guaranteed. The information was entered during April and May 2017 and drugs will have subsequently been randomly added during telephone demonstrations.
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|120 tablet (12 x 10 tablets)||£22.10|
|90 tablet (9 x 10 tablets)||£16.58|
|180 tablet (18 x 10 tablets)||£80.75|
|90 tablet (9 x 10 tablets)||£40.38|
|28 suppository (4 x 7 suppositories)||£40.01|